Books
-
Targeted Cancer Immune Therapy (2009)
Stimulation of the immune system's ability to control and destroy tumors cont- ues to be the goal of cancer immune therapy; but the scope has rapidly expanded; approaches are constantly updated; new molecules are continually introduced; and immune mechanisms are becoming better understood. This book has no intention of covering every aspect of immune therapy but rather focuses on the novelty of cancer immune therapy in an attempt to give readers an opportunity to absorb the new aspects of immune therapy from a single source. In this regard, three areas were selected: cytokine immune therapy, cell-based immune therapy, and targeted immune therapy. In each of these three sections, only the novel aspects of immune therapy were described instead of attempting to cover any historical achievement. In the first section, Cytokine Immune Therapy, the IL12 family, IL18, IL21, IL24, IL28, and IL29 were emphasized in regard to the an- tumor function and application in treating tumors. Most of these selected cyt- ines were discovered in last 10 years. In the second section, Cell-based Immune Therapy, the focus was engineering potent immune regulatory or effector cells such as dendritic cells, T cells, and stem cells. Cell engineering design is primarily based on the increased understanding of the interaction of tumor antigen-presenting cells, antigen- specific effector cells, and the tumor microenvironment.
$224.99 $219.99
-
Not Invited to the Party: How the Demopublicans Have Rigged the System and Left Independents Out in the Cold (2010)
Not Invited to the Party demonstrates how the dominant political parties--the Democrats and Republicans--have co-opted the system to their advantage. James Bennett examines the history and array of laws, regulations, subsidies and programs that benefit the two major parties and discourage even the possibility of a serious challenge to the Democrat-Republican duopoly. The American Founders, as it has been generally forgotten, distrusted political parties. Nowhere in the U.S. Constitution are parties mentioned, much less given legal protection or privilege. This provocative book traces how by the end of the Civil War the Republicans and Democrats had guaranteed their dominance and subsequently influenced a range of policies developed to protect the duopoly. For example, Bennett examines how the Federal Election Campaign Act of 1971 (as amended in 1974 and 1976), which was sold to the public as a nonpartisan act of good government reformism actually reinforced the dominance of the two parties. While focused primarily on the American experience, the book also considers the prevalence of two-party systems around the world (especially in emerging democracies) and the widespread contempt with which they are often viewed. Featuring incisive commentary on the 2008 election, and a foreword by third-party iconoclast, Ralph Nader, the book considers the potential of truly radical reform toward opening the field to vigorous, lively, contentious independent candidacies that might finally offer alienated voters a choice, not an echo.
$29.50 $24.50
-
Computational Methods for Counterterrorism (2009)
Modern terrorist networks pose an unprecedented threat to international security. The question of how to neutralize that threat is complicated radically by their fluid, non-hierarchical structures, religious and ideological motivations, and predominantly non-territorial objectives. Governments and militaries are crafting new policies and doctrines to combat terror, but they desperately need new technologies to make these efforts effective. This book collects a wide range of the most current computational research that addresses critical issues for countering terrorism, including: Finding, summarizing, and evaluating relevant information from large and changing data stores; Simulating and predicting enemy acts and outcomes; and Producing actionable intelligence by finding meaningful patterns hidden in huge amounts of noisy data. The book's four sections describe current research on discovering relevant information buried in vast amounts of unstructured data; extracting meaningful information from digitized documents in multiple languages; analyzing graphs and networks to shed light on adversaries' goals and intentions; and developing software systems that enable analysts to model, simulate, and predict the effects of real-world conflicts. The research described in this book is invaluable reading for governmental decision-makers designing new policies to counter terrorist threats, for members of the military, intelligence, and law enforcement communities devising counterterrorism strategies, and for researchers developing more effective methods for knowledge discovery in complicated and diverse datasets.
$114.99 $109.99
-
Pre-Columbian Foodways: Interdisciplinary Approaches to Food, Culture, and Markets in Ancient Mesoamerica (2010)
The significance of food and feasting to Pre-Columbian Mesoamerican cultures has been extensively studied by archaeologists, anthropologists and art historians. Foodways studies have been critical to our understanding of early agriculture, political economies, and the domestication and management of plants and animals. Scholars from diverse fields have explored the symbolic complexity of food and its preparation, as well as the social importance of feasting in contemporary and historical societies. This book unites these disciplinary perspectives -- from the social and biological sciences to art history and epigraphy -- creating a work comprehensive in scope, which reveals our increasing understanding of the various roles of foods and cuisines in Mesoamerican cultures. The volume is organized thematically into three sections. Part 1 gives an overview of food and feasting practices as well as ancient economies in Mesoamerica. Part 2 details ethnographic, epigraphic and isotopic evidence of these practices. Finally, Part 3 presents the metaphoric value of food in Mesoamerican symbolism, ritual, and mythology. The resulting volume provides a thorough, interdisciplinary resource for understanding, food, feasting, and cultural practices in Mesoamerica.
$334.00 $329.00
-
Engineering Design and Rapid Prototyping (2010)
"Engineering Design and Rapid Prototyping" offers insight into the methods and techniques that allow for easily implementing engineering designs by incorporating advanced methodologies and technologies. This book contains advanced topics such as feature-based design and process planning, modularity and rapid manufacturing, along with a collection of the latest methods and technologies currently being utilized in the field. The volume also: -Provides axiomatic design and solution methodologies for both design and manufacturing -Discusses product life cycle development and analysis for ease of manufacture and assembly -Offers applied methods and technologies in rapid prototyping, tooling and manufacturing "Engineering Design and Rapid Prototyping" will be extremely valuable for any engineers and researchers and students working in engineering design.
$184.00 $179.00
-
Hispanic Families at Risk: The New Economy, Work, and the Welfare State (2009)
In the United States, work is the key to economic success, as well as the major source of health care coverage and retirement security. While Europeans look to the State for these benefits, Americans for the most part do not. This system of employment-based benefits means that those disadvantaged in the labor market are also disadvantaged in terms of health care coverage and retirement security. The authors of this work examine the overrepresentation of Mexican Americans in low wage or service sector jobs, which rarely come with health insurance or retirement coverage. At all ages, Mexican Americans have lower rates of health insurance and retirement coverage than do other minority groups, such as African Americans or other Hispanic groups. Although employment in jobs that do not provide benefits is one major source of this disparity, other factors--including immigration history, citizenship status, and language proficiency--further block opportunities for upward mobility within the Mexican American population. In their analysis, the authors work to deemphasize the popular, cultural explanation for the economic disparities and focus on more practical, policy-based solutions. In each chapter, the authors identify and critique the factors that affect the economic security and health care access of individuals throughout the life course, suggesting policies for reform. This work will be of interest to anyone working in the fields of cultural studies, public health and the sociology of work. With the focus on real world causes for the problems as well as potential solutions, policy-makers will also find this informative book an essential resource.
$114.99 $109.99
-
Women in Early British and Irish Astronomy: Stars and Satellites (2009)
Careers in astronomy for women (as in other sciences) were a rarity in Britain and Ireland until well into the twentieth century. The book investigates the place of women in astronomy before that era, recounted in the form of biographies of about 25 women born between 1650 and 1900 who in varying capacities contributed to its progress during the eighteenth, nineteenth and early twentieth centuries. There are some famous names among them whose biographies have been written before now, there are others who have received less than their due recognition while many more occupied inconspicuous and sometimes thankless places as assistants to male family members. All deserve to be remembered as interesting individuals in an earlier opportunity-poor age. Placed in roughly chronological order, their lives constitute a sample thread in the story of female entry into the male world of science. The book is aimed at astronomers, amateur astronomers, historians of science, and promoters of women in science, but being written in non-technical language it is intended to be of interest also to educated readers generally.
$114.99 $109.99
-
Handbook of Pediatric Chronic Pain: Current Science and Integrative Practice
The purpose of this text is to provide not only the science and current knowledge of pediatric pain management but a rationale for intervention. The book is ground-breaking in that it provides pearls for the recognition and management of multiple childhood chronic pain syndromes. Also, uncommon yet confounding issues such as pain management for epidermolysis bullosa are adequately addressed. Concerns unique to pediatric patients are reviewed. While there are no firm standards in pediatric chronic pain, a care plan is offered to help guide practitioners when possible. The book will consist of 24 chapters, many co-written by a physician and a psychologist. Chapter 1 covers the history of pediatric chronic pain, the advancement pediatric pain as a clinical subspecialty, development of pediatric pain clinics, and characterization of the common pain syndromes. Chapters 2-4 cover, respectively, the research on early pain exposure and neuroplasticity, theories on the common adolescent pain syndromes, and the demographics of chronic pain in children. Chapters 5-16 discuss approaches to assessment and intervention for specific pediatric and adolescent pain syndromes. Chapters 17-23 address interventional techniques such as therapeutic blocks, neurablation, implantable systems, physical therapy, complementary therapy, and pharmacology including opioid tolerance. The final chapter discusses the role of the nurse practitioner in pediatric chronic pain.
$174.99 $169.99
-
Visual Complexity and Intelligent Computer Graphics Techniques Enhancements (2009)
This book offers the latest research in Intelligent Scene Modeling Information Systems. It uses three main notions to explore improvements in various areas of computer graphics: Artificial Intelligence, Viewpoint Complexity, and Human Intelligence.
$114.99 $109.99
-
Explorations in Harmonic Analysis: With Applications to Complex Function Theory and the Heisenberg Group (2009)
This text on modern harmonic analysis provides an introduction to the subject in the context in which it is actually applied, in particular, through complex function theory and partial differential equations. The exposition begins with the fundamentals of Fourier analysis, complex function theory, and integral operators and further introduces students to cutting-edge ideas about the Heisenberg group.
$59.99 $54.99
-
Chemical Communication in Crustaceans
The crustaceans are ecologically and economically important organisms. They constitute one of the dominant invertebrate groups on earth, particularly within the aquatic realm. Crustaceans include some of the preferred scientific model organism, profitable aquaculture specimen, but also invasive nuisance species threatening native animal communities throughout the world. Chemoreception is the most important sensory modality of crustaceans, acquiring important information about their environment and picking up the chemical signals that mediate communication with conspecifics. Significant advances have been made in our understanding of crustacean chemical communication during the past decade. This includes knowledge about the identity, production, transfer, reception and behavioral function of chemical signals in selected crustacean groups. While it is well known that chemical communication is an integral part of the behavioral ecology of most living organisms, the intricate ways in which organisms allocate chemicals in communication remains enigmatic. How does the environment influence the evolution of chemical communication? What are the environmental cues that induce production or release of chemicals? How do individuals economize production and utilization of chemicals? What is the importance of molecule specificity or mix of a molecule cocktail in chemical communication? What is the role of chemical cues in multimodal communication? How does the ontogenetic stage, the sex or the physiological status of an individual affect its reaction to chemical cues? Many of these questions still represent important challenges to biologists.
$334.99 $329.99
-
Role of Genetics in Breast and Reproductive Cancers (2010)
This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
$224.99 $219.99
You have seen 540 out of 1405 products